When you cook meat, the collagen fibers in the flesh contract and squeeze liquid out of the meat regardless of the cooking temperature. With high heat, the liquid boils away immediately and you never see it, while at lower temperatures the liquid accumulates in the pan. The sizzle you hear over high heat is in fact the sound of that liquid rapidly boiling away. When you cook meat, the collagen fibers in the flesh contract and squeeze liquid out of the meat regardless of the cooking temperature. With high heat, the liquid boils away immediately and you never see it, while at lower temperatures the liquid accumulates in the pan. The sizzle you hear over high heat is in fact the sound of that liquid rapidly boiling away.