Table sugar (aka sucrose or cane/beet sugar) is made of equal parts of two simpler sugars, glucose and fructose. When digested, it breaks down and your body absorbs the glucose and fructose. HFCS also contains glucose and fructose but in a slightly different proportion, most commonly 55% fructose and 45% glucose (hence, high fructose). So, ingesting HFCS instead of table sugar gives you 5% more fructose and 5% less glucose. To listen to some people, this is the end of civilization as we know it! Yet, many studies have been conducted comparing HFCS to table sugar, and they have failed to turn up any meaningful differences in their effects on the body, including insulin, triglycerides, blood glucose, liver function, or appetite-related hormones.